Diabetes Mellitus Cat
Diabetes Mellitus Cat
Diabetes mellitus is the second most common endocrine disease seen in cats.
Diabetes mellitus is one of the most common endocrine disorders in middle-aged to older cats where it has been estimated to affect one in 230 cats. Diabetes can be diagnosed in any breed, age or gender but more commonly seen in older, overweight male cats.
Diabetes occurs when the pancreas does not produce effective levels of insulin. Insulin is required to process sugars, fats and proteins into energy so without it, blood levels of sugar are too high. Body cells become affected as they don't receive adequate nourishment and, therefore, bodily systems start to break down.
Although a serious condition that may require a strict and long-term commitment, it doesn't have to be as difficult as it sounds. Unlike diabetic dogs, the condition can be transient meaning that with aggressive, short-term treatment, weight loss and diet changes, the cat may be cured.
Diabetes mellitus or simply diabetes is a chronic condition caused by a deficiency or resistance to insulin. Insulin is necessary for the body to turn glucose into energy.
Common signs of diabetes:
Predisposing factors:
Types of Diabetes mellitus
Type I |
The failure to produce insulin Life-long disease More commonly seen in dogs |
Type II |
Insufficient product of insulin Often related to obesity Can be a transient disease More commonly seen in cats |
Diagnosis is based on physical examination, laboratory tests and urinalysis. High blood sugar and high levels of glucose in the urine are often found.
Treatment often requires numerous types of lifestyle changes such as medical (insulin injections) and dietary changes. Regular visits to the veterinarian, blood tests and urine tests are required.
Diabetic cats are managed in a similar way to humans with diabetes. In most cases, affected cats require insulin therapy at home once stabilised in hospital. The starting dose is often small and given 1 or 2 times daily with close monitoring of the cat's appetite, water consumption and urinating habits. Occasionally a series of glucose blood tests (referred to as a blood glucose curve) is performed in the hospital over a day to assess the absorption and metabolism of the insulin.
Management of diabetes:
Your pet will require a recheck approximately days to a week after diagnosis and start of the treatment, then depending on how well he/she stabilises less frequent rechecks, e.g. monthly to 3 monthly check ups are needed once on a stable dose. As blood glucose levels can increase dramatically during a stay in the hospital, home monitoring is extremely important. In view of the possible remission, careful monitoring of your diabetic pet is required.
Diet therapy is extremely important in the management of Diabetes in cats.
Feeding a recommended high protein and low carbohydrate diet is also extremely important in controlling the disease. The goal is to stabilise the pet by controlling clinical signs and avoiding low blood sugar. In rare cases, a strict diet alone may control Diabetes in cats.
Cats can experience diabetic remission, particularly if well controlled initially with insulin and a strict diet. It has been estimated that 80% of cats go into remission when treated immediately after diagnosis and won't require lifelong insulin treatment.
A diabetic pet needs its insulin to survive. But, too much insulin can also be deadly. Too much insulin can result in hypoglycaemia or a low blood sugar level. This can occur when a cat accidentally receives a too high a dose, too many doses or is not eating. Hypoglycaemia is also possible if Diabetic Remission has not been detected early enough. Early signs of low blood sugar include weakness, lethargy or disorientation. If this is to happen, seek veterinary attention immediately. You may be advised to put a small amount of sugar syrup on the cat's gums to be able to safely get the cat to the hospital.
Be aware, if your diabetic cat has been well controlled but starts to drink more again, do not just increase the insulin dose yourself, but visit your vet instead. Sometimes, when the blood sugar level drops below normal, other hormones in the body can kick in to temporarily raise the blood sugar level as a protection mechanism. Increasing the insulin dose in this case can be detrimental.
If your pet experiences any of the following, seek veterinary attention immediately:
Tips to help prepare and give Insulin injections:
Always follow the environmental laws for the disposal of medical waste material or bring any used needles and syringes back into the veterinary clinic for disposal.
Alt, N., Kley, S., Haessig, M., Reusch, C.E., Day-to-day variability of blood glucose concentration curves generated at home in cats with diabetes mellitus J Am Vet Med Assoc 2007; 230(7): 1011-1017
Appleton, D.J., Rand, J.S., Sunvold, G.D., Insulin sensitivity decreases with obesity, and lean cats with low insulin sensitivity are at greatest risk of glucose intolerance with weight gain. J Feline Med Surgery 2001; 3(4): 211-28
Bailiff, N.L., et al., Frequency and risk factors for urinary tract infection in cats with diabetes mellitus. J Vet Intern Med 2006; 20(4):850-5
Baral, R., Rand, J.S., Catt, M Farrow, H. A., Prevalence of feline diabetes mellitus in a feline private practice. J. Vet. Intern. Med. 2003; 17: 433
Bloom, F., Diabetes Mellitus in a Cat. New England J Med 1937; 217:395-398
Cowan, S.M., Bunch, S.E., Oral Antidiabetic drugs for cats. Compendium 2001; 23(7):633-642
Frank G., Anderson W., Pazak H, Hodgkins E., Ballam J., Laflamme D., Use of a high-protein diet in the management of feline diabetes mellitus. J Am Vet Med Assoc 2000; 212 (3): 1082-1088
Greco DS, Broussard JD, Peterson ME. Insulin therapy. Vet Clin North Am Small Anim Pract 1995;25:677-689
Marshall R. D., Rand J.S., Morton J.M., Treatment of newly diagnosed diabetic cats with glargine insulin improves glycaemic control and results in higher probability of remission than protamine zinc and lente insulins. J Feline Med Surg. 2009;11(8):683-91
Moise N.S., Reimers T.J., Insulin therapy in cats with diabetes mellitus. J Am Vet Med Assoc. 1983 Jan15;182(2):158-64
Nelson, R. W., et al., Effect of dietary insoluble fiber on control of glycemia in cats with naturally acquired diabetes mellitus. J Am Vet Med Assoc 2000;216(7):1082-1088
Panciera, D. L., Thomas, C. B., Eicker, S. W. & Atkins, C. E., Epizootiological patterns of diabetes mellitus in cats: 333 cases (1980–1986). J. Am. Vet. Med. Assoc. 1990;197: 1504–1508.
Salgado D, Reusch C, Spiess B., Diabetic cataracts: different incidence between dogs and cats. Schweiz Arch Tierheilkd. 2000;142(6):349-53
Webb C. Diabetes mellitus without complication – Dogs. In Blackwell’s Five-Minute Veterinary Consult: Canine & Feline. Eds. Tilley LP, Smith FWK. 2007, 4th Blackwell Publishing, Ames, Iowa. pp. 376-377.
McCann TM, Simpson KE, Shaw DJ, et al. Feline diabetes mellitus in the UK: The prevalence within an insured cat population and a questionnaire-based putative risk factor analysis. J Feline Med Surg 2007; 9: 289-299.